Early amyloid β-protein aggregation precedes conformational change
نویسندگان
چکیده
منابع مشابه
Early amyloid β-protein aggregation precedes conformational change.
The aggregation of amyloid-β protein (1-42) is studied at experimental concentrations using all-atom molecular dynamics simulations. We observe a fast aggregation into oligomers without significant changes in the internal structure of individual proteins. The aggregation process is characterized in terms of transition networks.
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ژورنال
عنوان ژورنال: Chem. Commun.
سال: 2014
ISSN: 1359-7345,1364-548X
DOI: 10.1039/c3cc48704k